EBioMedicine: A new way to quickly diagnose severe sepsis

Release date: 2014-10-30

A recent study found that researchers at the University of British Columbia have developed a new test that will help doctors predict whether a patient will develop severe sepsis within an hour so they can begin treatment immediately.

Sepsis is a syndrome caused by an infection that causes organ failure and the deaths of up to five million people each year. There are approximately 18 million sepsis patients worldwide each year.

This finding can reduce the time to diagnose patients with sepsis and increase their feedback on efficacy.

"We found a genetic marker that is associated with the diagnosis of sepsis and subsequent organ failure," Bob Hancock said. “Once the patient goes to the emergency room, we can test this genetic marker.” It usually takes 24 to 48 hours for a patient to be diagnosed, but with this new test, the doctor can start treating the patient right away.

A new test on genetic markers was recently published in the journal EBioMedicine, which takes only one hour to diagnose 96% of patients in the early stages of sepsis.

The findings also show misunderstandings about the disease. Until now, sepsis is still considered an inflammatory disease, but more than 30 anti-inflammatory drugs in clinical trials have failed in the treatment of sepsis. The genetic markers found by Hancock and his colleagues are associated with recombinant cellular immunosuppressive agents, but it is not a good idea to treat inflammatory sepsis with this particular cellular recombinant immunosuppressive agent.

Source: Bio Valley

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