The "engine" of technological innovation in the medical field

The "engine" of technological innovation in the medical field

February 15, 2015 Source: Family Planning Commission

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According to "Long-term Scientific and Technological Development Plan (2006-2020)" deployment, organized by the National Health and Family Planning Commission and the General Logistics Department of the Ministry of Health led by "significant Drug Discovery" science and technology major projects (hereinafter referred to as "special drugs") by the State Council approved in August 2008 to start the implementation, focusing on major diseases for cancer, cardiovascular and other 10 categories (species), a group of independent research and technological innovation drugs, improve national drug innovation system, enhance innovation capability, accelerate our country by a drug The transformation of imitation to creation, from a big pharmaceutical country to a strong country.

Under the unified leadership of the State Council, the new drug special project has always been oriented to the main battlefield of population health. It has been guided by major disease prevention and industrial development needs. After six years of implementation, it has achieved fruitful results and provided a strong technical support for the development of China's medical and health undertakings.

The results of new drug research and development are remarkable. Strengthened against major diseases innovative drug research and development, has total access to new drug certificate 85, 118 clinical documents of approval. The world's first Sabin strain polio inactivated vaccine was approved for marketing, marking China's international advanced level in this research field; the world's first listed oral treatment of peripheral T- cell lymphoma drug cidabenamine was approved for marketing; Apatinib, a small molecule anti-angiogenic targeting drug for the treatment of advanced gastric cancer, was approved for marketing, filling the gap in the field.

The accessibility of clinical medications is significantly improved. Closely combined with the clinical drug demand, completed the technical transformation of more than 200 kinds of drugs, of which 80 varieties are the "National Essential Drugs Catalogue" variety, significantly improving the accessibility of clinical drugs, and providing protection for deepening medical reform . Especially in this year's Ebola hemorrhagic fever epidemic prevention and control, viral nucleic acid diagnostic reagents, antibodies and small molecule drugs, vaccines and other aspects have achieved important results, some drugs have been equipped with my aid non-medical team.

The construction of the innovation system has continued to increase. The innovation ability of the knowledge innovation system based on universities and research institutes and the technological innovation system based on enterprises has been continuously strengthened. The drug innovation technology system consisting of comprehensive technology platform, safety evaluation and clinical trial technology platform, and enterprise incubation base was further improved, which closely links the source innovation and industrial promotion , and provides important for the scientific and technological innovation in China's pharmaceutical field. Technical Support. For example, the China National Institute for Food and Drug Control has been approved by the WHO for the first bioproduct evaluation cooperation center in developing countries; the national compound sample library has a total inventory of 1.858 million, ranking first in Asia.

The transformation and development of the pharmaceutical industry. Driven by new drug support and innovation, 15 high-tech parks guide social resources to focus areas, and various innovative factors have concentrated on the formation of a number of pharmaceutical industry clusters in Beijing, Shanghai, Zhejiang, Jiangsu, etc. Local industrial restructuring and economic transformation and development. The average growth rate of the pharmaceutical industry in the past five years ranks first among all industrial sectors. The number of enterprises with a pharmaceutical industry output exceeding 10 billion has increased from 2 in 2008 to 11 in 2014 .

The achievements in the construction of the talent team are outstanding. Since the implementation of the new drug combination of a number of special active in the domestic production line of scientific research talents, attracted about 200 national "people plan" to introduce talents and more than 3000 overseas high-level talents, formed a mainly middle-aged 10 More than 10,000 people's research and development team.

So far, the research and development results supported by the new drug have won more than 40 National Natural Science Awards and National Science and Technology Progress Awards. Among them, in 2014 , they won 7 National Science and Technology Progress Awards, including 1 first prize and 6 second prizes.

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