According to Shenguo, the largest overseas medical service provider in China, in early 2015, US President Barack Obama announced in his 2015 State of the Union speech that the United States will invest $215 million to launch a program called Precision Medicine.
He said that the United States has completed the Human Genome Project and eliminated polio, which means that the United States has made human medicine a new era, and then it is committed to curing diseases such as cancer and diabetes, so that everyone can get it. Personalized information and medical care that protects the health of yourself and your family.
President Obama has long had a strong belief that science offers great potential for improving health. The new plan he is now announcing is to accelerate the process of a new era of precision medicine . We believe that the time is to make this once-imagined plan a reality, the National Institutes of Health (NIH) and other partners will be committed to the realization of this vision.
1, the tumor is included in the preferred target
In fact, the concept of precision medicine – the prevention and treatment strategy for individuals – is not new. For example, clinically, blood transfusion has been guided by blood type for more than a century, especially in recent years, the establishment of large-scale biological databases (such as human genome sequencing, proteomics, metabolomics, genomics), and mobile medical technology, large With the advent of data computing tools, the application prospects of this concept have been significantly improved. There is an urgent need for a systematic plan to research and practice the creative tools of precision medicine to build evidence-based medical data that guides clinical needs.
The upcoming precision medicine program will consist of two parts: a focus on cancer research's near-term planning and long-term planning to generate knowledge for a full range of health and disease. Thanks to advances in basic research, relevant information, including molecular biology, genomics and bioinformatics, is within reach. In addition, with the growing convergence of social media and mobile devices, the public's enthusiasm for participating in various medical research is growing.
In terms of short-term influence, cancer is clearly the first choice for precision medicine. As a common disease, cancer is the main cause of death in the United States and the world. With aging, its incidence is constantly increasing. rise. The lethality of cancer and the toxic side effects of anticancer treatment make people talk about cancer discoloration. Studies have found that many molecular lesions are one of the triggers for cancer, suggesting that cancers have their own genetic markers, including tumor-specific molecular features and shared molecular features. Although cancer is mainly caused by accumulation of genomic damage during the life cycle, genetically acquired genetic variation increases the risk of cancer, and sometimes even plays a decisive role.
This new understanding of carcinogenic mechanisms has begun to affect cancer risk assessment, diagnostic categories and treatment strategies, and has spawned many drug and antibody design therapies for specific oncogenic molecules. Some targeted therapies for cancer have been (or are being) Development, some of the effects are good, and some have significant effects. Among them, immunotherapy is considered to be a promising therapy, and there are indications that molecular markers may be a major indicator of its prognosis.
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