Thin column five plus
(1) Anti-inflammation: Aqueous liquid of Quejia Wujiao decoction and n-butanol extract can significantly inhibit foot swelling of rats caused by carrageenan, and can also significantly inhibit the proliferation of granulation tissue of mouse cotton balls after continuous administration for one week. The short-stem acanthopanax extracts significantly impaired paw edema in rats caused by carrageenan, egg white, and formaldehyde, and had a significant inhibitory effect on airbag edema and cotton granule proliferation in mice caused by croton oil, but also significantly inhibited rats. Adjuvant joint swelling and immune complex mediated allergic inflammatory response. It is currently believed that the anti-inflammatory effects of Acanthopanax senticosus are mainly caused by reducing the release of inflammatory mediators and inhibiting their inflammatory effects.
(2) Effect on immune function: Acanthopanax quinquefolius water decoction and alcohol-sinking liquid can inhibit the immune function, and can significantly reduce the percentage of phagocytic and phagocytic index of mouse peritoneal macrophages, and significantly inhibit mouse spleen antibody-forming cells. The experimental study of the hepatic heart transplantation in neonates showed that the anti-rejection effect of A. quinquefolium increased the average survival time of transplanted myocardium significantly.
The total saponins and polysaccharides of Acanthopanax senticosus can improve the immune function of the body. Gavage administration can promote the phagocytic function of the reticuloendothelial system in mice, increase the clearance rate of serum carbon and increase the serum antibody concentration of mice. Humoral immune function.
(3) Sedation and analgesia: Fine Quercetin Plus extract exerts a synergistic effect on subthreshold pentobarbital sodium, which significantly prolongs sleep in mice. The n-butanol extract and the short-five extract of Acanthopanax senticosus can increase the pain threshold and have obvious analgesic effect.
(4) Cadmium-resistant mutagenicity and anti-stress effects: Cadmium is a heavy metal inducer that has a strong mutagenic effect on germ cells and can induce sperm abnormalities in mice and increased micronuclei in bone marrow cells. Penicillium acnes extract mice administered for 5 weeks continuously reduced cadmium-induced sperm abnormalities and increased micronuclei in bone marrow cells with inhibitory rates of 63.9% and 74.3%, respectively. The total saponins of A. quinquefolium can significantly prolong the swimming time, the survival time of heat stress and the tolerance to hypoxia.
(5) Promoting nucleic acid synthesis: The addition of aqueous extracts of alcohol to the stem of the fifth column increased the DNA synthesis in the hepatic and spleen cells of young mice, and Pentabarium polysaccharides promoted the DNA synthesis of hepatocytes in mice with toxic hepatic injury in the CCI4 team.
(6) Sex hormone-like effects: Quaternary pentasaccharides have sex hormone-like effects, and continuous administration for 7 days can promote the development of minor sex organs in rats and increase the weight of the testis, prostate and seminal vesicles. The addition of water extracts of red hair and five species can also promote the development of young rats.
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