Concerned about the World Hepatitis Day: about 10% of Hepatitis B patients can be cured

Hualong News at 20:13 on July 27th (Reporter Huang Yu) is the sixth World Hepatitis Day on the 28th. In the opinion of many people, hepatitis B is a chronic disease that will never be able to escape the fate of taking medicine. Professor Zhang Dazhi, director of the Department of Infectious Diseases at the Second Affiliated Hospital of Chongqing Medical University, pointed out that this is actually a wrong view. By receiving scientific and standardized treatment, the condition of chronic hepatitis B patients can be effectively controlled, and about 10% of hepatitis B patients can be cured.

Hepatitis B is one of the common chronic infectious diseases and has become one of the important public health problems in China. At present, the positive carrying rate of hepatitis B virus surface antigen in China is about 7.18%. In Chongqing, there are about 473,800 chronic hepatitis B patients, which means that for every 100 Chongqing people, there is at least one chronic hepatitis B patient.

"In clinical practice, we have found that many people have misunderstandings about hepatitis B, causing some patients to go to bed for medical treatment and have not received timely and effective treatment," said Zhang Dazhi. According to incomplete statistics, the incidence of hepatitis B in Chongqing is only 4.1%, which is lower than the national average. Average.

In fact, the “Guidelines for the Prevention and Treatment of Chronic Hepatitis B” in 2015 clearly defined the endpoint of treatment for hepatitis B as being divided into three levels. The first is the acceptable end point of treatment, that is, the hepatitis B virus fell to undetectable levels. This stage cannot be stopped, once stopped. Drugs are very easy to relapse; Second, long-lasting virological response and e antigen seroconversion after discontinuation, that is, after the antiviral treatment to obtain a lasting "big three positive" to "small three positive", for the satisfaction of the end point of treatment; The ideal therapeutic endpoint, the persistence of surface antigen clearance after discontinuation, with or without surface antigen serological conversion, is usually referred to as a "clinical cure."

“In other words, about 10% of hepatitis B patients can be cured.” Zhang Dazhi said that some hepatitis B patients can achieve drug withdrawal without recurrence, which brings great hope for hepatitis B patients.

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